学习经历：

2005.09-2009.06 贵州大学 农学 学士

2009.09-2012.06 西北农林科技大学 作物遗传育种 硕士

2012.10-2017.07 德国法兰克福大学 生物学 博士

主要工作经历与任职情况：

2017.12-2023.09 特拉维夫大学 博士后

2023.12-至今 beat365官方最新版 教授

2023.12-至今 武汉大学杂交水稻全国重点实验室 PI

主要科研奖励和个人荣誉：

2023年入选“国家海外高层次人才计划（青年项目）”

2018年入选以色列优秀“PBC fellowship” 博士后项目

主持课题项目：

2023年 国家高层次人才计划青年项目 主持

主要研究领域：

　　植物激素是一组由植物产生的低浓度小信号分子，能够在远端部位移动和发挥作用。激素稳态对于平衡植物生长和发育至关重要，并且在多个层面上受到调节，包括激素生物合成、降解代谢、感知和转运。激素转运体对植物激素发挥作用至关重要，这突出表现在它们的功能丧失导致严重的生长和发育缺陷。因此，植物激素转运蛋白对精确调控其生长发育至关重要。但是，转运蛋白家族的潜在功能冗余性严重的限制了植物转运蛋白遗传与功能的研究。
　　本课题组对调节植物激素以及主要矿质营养转运机制的分子因素感兴趣。本课题组已构建能在基因组规模克服功能冗余的多靶标CRISPR文库，结合正向遗传筛选，采用分子生物学、化学生物学和共聚焦显微镜成像等技术，聚焦于植物激素和主要营养元素转运蛋白的鉴定及其转运机制的剖析研究。

代表性论文（#并列第一作者，*通讯作者）：

Yangjie Hu; Priyanka Patra; Odelia Pisanty; Anat Shafir; Zeinu Mussa Belew; Jenia Binenbaum; Shir Ben Yaakov; Bihai Shi; Laurence Charrier; Gal Hyams; Yuqin Zhang; Maor Trabulsky; Omer Caldararu; Daniela Weiss; Christoph Crocoll; Adi Avni; Teva Vernoux; Markus Geisler; Hussam Hassan Nour-Eldin; Itay Mayrose; Eilon Shani. Multi-Knock—a multi-targeted genome-scale CRISPR toolbox to overcome functional redundancy in plants. Nature Plants, 2023, 9,572-587.

Yangjie Hu* and Eilon Shani*. Cytokinin activity – transport and homeostasis at the whole plant, cell, and subcellular levels. New Phytologist, 2023.

Jian Chen#; Yangjie Hu#; Pengchao Hao; Tashi Tsering; Jian Xia; Yuqin Zhang; Ohad Roth; Maria F Njo; Lieven Sterck; Yun Hu; Yunde Zhao; Danny Geelen; Markus Geisler; Eilon Shani; Tom Beeckman; Steffen Vanneste. ABCB-mediated auxin transport in outer root tissues regulates lateral root spacing in Arabidopsis. EMBO Reports, 2023, e56271.

Yangjie Hu; Moutasem Omary; Yun Hu; Ohad Doron; Lukas Hoermayer; Qingguo Chen; Or Megides; Ori Chekli; Zhaojun Ding; Jiří Friml; Yunde Zhao; Ilan Tsarfaty; Eilon Shani. Cell kinetics of auxin transport and activity in Arabidopsis root growth and skewing. Nature Communications, 2021, 12(1):1657.

Yangjie Hu; Anida Mesihovic; Jose M. Jimenez-Gomez; Sascha Roth; Philipp Gebhardt; Daniela Bublak; Arnaud Bovy; Klaus-Dieter Scharf; Enrico Schleiff and Sotirios Fragkostefanakis. Natural variation in HsfA2 pre‐mRNA splicing is associated with changes in thermotolerance during tomato domestication. New Phytologist, 2020, 225(3), 1297-1310.

Yangjie Hu; Sotirios Fragkostefanakis; Enrico Schleiff; Stefan Simm. Transcriptional basis for differential thermosensitivity of seedlings of various tomato genotypes. Genes, 2020, 11(6), 1-21.

Yana Kazachkova; Itay Zemach; Sayantan Panda; Samuel Bocobza; Andrii Vainer; Ilana Rogachev; Yonghui Dong; Shifra Ben-Dor; Dorottya Veres; Christa Kanstrup; Sophie Konstanze Lambertz; Christoph Crocoll; Yangjie Hu; Eilon Shani; Simon Michaeli; Hussam Hassan Nour-Eldin; Dani Zamir; Asaph Aharoni; The GORKY glycoalkaloid transporter is indispensable for preventing tomato bitterness, Nature plants, 2021, 7: 468-480

Tingting Ding; Feng Zhang; Junxia Wang; Fengxia Wang; Jiajia Liu; Chuantian Xie; Yangjie Hu; Eilon Shani; Xiangpei Kong; Zhaojun Ding; Huiyu Tian; Cell‐type action specificity of auxin on Arabidopsis root growth, The Plant Journal, 2021, 106(4): 928-941

Sotirios Fragkostefanakis; Stefan Simm; Asmaa El‐Shershaby; Yangjie Hu; Daniela Bublak; Anida Mesihovic; Katrin Darm; Shravan Kumar Mishra; Bettina Tschiersch; Klaus Theres; Christian Scharf; Enrico Schleiff; Klaus‐Dieter Scharf; The repressor and co‐activator HsfB1 regulates the major heat stress transcription factors in tomato, Plant Cell Environ, 2018, 42(3): 874- 890

Sotirios Fragkostefanakis; Anida Mesihovic; Stefan Simm; Marine Josephine Paupière; Yangjie Hu; Puneet Paul; Shravan Kumar Mishra; Bettina Tschiersch; Klaus Theres; Arnaud Bovy; Enrico Schleiff; Klaus-Dieter Scharf; HsfA2 Controls the Activity of Developmentally and Stress Regulated Heat Stress Protection Mechanisms in Tomato Male Reproductive Tissues, Plant Physiology, 2016, 170(4): 2461-2477

Mario Keller; Yangjie Hu; Anida Mesihovic; Sotirios Fragkostefanakis; Enrico Schleiff; Stefan Simm; Alternative splicing in tomato pollen in response to heat stress, DNA Research, 2016, 24(2): 205-217

Sotirios Fragkostefanakis; Anida Mesihovic; Yangjie Hu; Enrico Schleiff; Unfolded protein response in pollen development and heat stress tolerance, Plant Reprod, 2016, 29(1-2): 81-91

Jieun Shin; Shenxiu Du; Nora Bujdoso; Yangjie Hu; Seth J. Davis; Overexpression and loss-of-function at TIME FOR COFFEE results in similar phenotypes in diverse growth and physiological responses, J. Plant Biol, 2013, 56(3): 152-159

招生招聘：

· 课题组招聘博士后和科研助理，热忱欢迎具有植物学，遗传学，农学，发育生物学或生物信息学等相关背景的有志青年入驻加盟。简历初审合格者将邮件通知面试，对申请者信息严格保密。

· 热忱欢迎对本研究方向有兴趣的同学报考博士研究生和硕士研究生（每年接收2名博士生，2-3名硕士生）；

· 欢迎有志于科研的本科生提前进组参加科学训练项目。